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Four stages of knee osteoarthritis

Medically reviewed by
Aaron Reichman, MD, Interventional Radiologist
Reviewed October 2026

Knee osteoarthritis develops in four stages, and knowing which one you are in helps explain your symptoms and your options. Osteoarthritis is the most common form of arthritis, affecting an estimated 33 million adults in the United States, and the knee is one of the joints it affects most often.[1] As the cartilage that cushions the knee joint wears down, the condition progresses from minor, often unnoticed changes to significant, constant discomfort. Understanding where your knee falls in that progression can help you and your care team decide what steps make sense next.

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What Is Knee Osteoarthritis?

Osteoarthritis of the knee is a specific type of arthritis in which cartilage in the knee joint begins to deteriorate. The cartilage loss narrows the space between bones, causing the bones to rub against each other. Overgrowths at the edge of the knee bones, known as bone spurs, may also occur.

Common Symptoms of Knee Osteoarthritis

As the disease progresses, knee osteoarthritis can bring on the following symptoms:

  • Aching or throbbing pain
  • Swelling or tenderness
  • Joint stiffness or instability
  • Locking or popping sensations
  • Loss of flexibility or range of motion

Understanding the Kellgren-Lawrence Grading Scale

Physicians typically describe knee osteoarthritis severity using the Kellgren-Lawrence grading scale, a system based on X-ray findings.[2] The scale runs from Grade 0, a knee with no visible signs of osteoarthritis, through Grade 4, a knee with severe cartilage loss. Grading looks at a few specific features: the width of the joint space between bones, the presence of osteophytes (bone spurs), and changes to the bone surface itself. This article uses the four main stages patients are usually told about, Stages 1 through 4, which correspond to Kellgren-Lawrence Grades 1 through 4.

Stage 1: Minor Knee Osteoarthritis

Stage 1 is the earliest point at which changes become visible on an X-ray. Cartilage has only just begun to wear, and any bone spur formation is very small.

Symptoms of Stage 1 Knee Osteoarthritis

Most people at Stage 1 feel little to no pain. Some notice brief stiffness after sitting for a while or occasional aching after an unusually active day, but daily activities are rarely affected. Many people do not realize anything has changed in the joint at all.

What Imaging Shows at Stage 1

X-rays at this stage show possible, minor osteophyte formation with the joint space still essentially intact. Because symptoms are so mild, Stage 1 is more often discovered incidentally, such as during imaging for an unrelated knee concern, than through a patient-reported complaint.

Stage 2: Mild Knee Osteoarthritis

By Stage 2, imaging shows more definite bone spur growth, though the joint space usually still looks close to normal.

Symptoms of Stage 2 Knee Osteoarthritis

Stiffness and mild discomfort become more noticeable at this stage, particularly after periods of rest or at the end of an active day. Some people start to notice the knee more during stairs, kneeling, or long walks, though pain is typically intermittent rather than constant.

Staying Active With Stage 2 Knee Osteoarthritis

Gentle, low-impact movement, such as walking, swimming, or cycling, is generally recommended over extended rest at this stage. Movement helps maintain joint mobility and keeps the surrounding muscles strong, which supports the knee. Short rest breaks during flare-ups are reasonable, but long stretches of inactivity tend to make stiffness worse rather than better. Reviewing your knee osteoarthritis causes can also help you identify habits or risk factors worth adjusting early.

Stage 3: Moderate Knee Osteoarthritis

Stage 3 marks a clearer turning point. Cartilage loss becomes more substantial, and the joint space narrows further on imaging.

Symptoms of Stage 3 Knee Osteoarthritis

Pain at Stage 3 tends to be more frequent and more noticeable during everyday movement, including walking, bending, and climbing stairs. Swelling after activity becomes more common, and stiffness after sitting may take longer to ease. Some people also notice a grinding or catching sensation as the joint moves.

How Stage 3 Affects Daily Movement

Because pain and swelling are more consistent at this stage, daily tasks like standing for long periods, squatting, or carrying groceries can become harder to manage comfortably. This is often the point where conservative measures alone start to feel less effective, which is why many patients begin exploring additional options around Stage 3.

Stage 4: Severe (End-Stage) Knee Osteoarthritis

Stage 4 is the most advanced point on the Kellgren-Lawrence scale and is often referred to as bone-on-bone knee arthritis, since the cartilage that once cushioned the joint has worn down significantly or nearly completely.[3]

Symptoms of Stage 4 Knee Osteoarthritis

Stage 4 typically involves more constant pain, including discomfort that may continue even at rest or disrupt sleep. Stiffness is more persistent, swelling is common, and many people notice a reduced range of motion along with a grinding sensation during movement. Daily activities such as walking, climbing stairs, or standing from a seated position often become more difficult.

What Makes Stage 4 “End-Stage” Knee Osteoarthritis

“End-stage” describes the point on the grading scale where cartilage loss is at its most advanced and joint space is severely narrowed or gone. It is a description of what imaging shows, not a prediction of how much pain any individual will have. Research has clarified that joint inflammation, not cartilage loss alone, contributes substantially to pain at this stage, which has implications for which treatments may help. You can read more detail in our overview of bone-on-bone knee arthritis.

Walking With Advanced Knee Osteoarthritis

Complete inactivity is generally not recommended at Stage 4, since avoiding movement allows the muscles supporting the knee to weaken over time. Gentle, low-impact movement, paced to your comfort level and ideally guided by a physical therapist or specialist, is usually a better approach than prolonged rest.

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Treatment Options by Stage of Knee Osteoarthritis

Treatment approaches generally shift as the stages progress, though the right option always depends on an individual evaluation rather than the stage number alone. Various treatment options address pain and swelling from osteoarthritis in the knee. The best treatment for you will depend on the extent of your condition.  

Treatment Options  Stage(s) 
Lifestyle changes, physical therapy, weight management  1 
Medications, steroid injections  1, 2, 3 
Genicular artery embolization (GAE)  2, 3, 4 
Knee replacement surgery  4 

 

Conservative Care for Early Stages

At Stages 1 and 2, treatment often starts with weight management, activity modification, and physical therapy. These approaches can help manage mild symptoms and may help slow how quickly the condition progresses, though they do not reverse existing cartilage wear.

Minimally Invasive Options for Moderate to Advanced Stages

When conservative care is no longer providing enough relief, typically somewhere between Stage 2 and Stage 4, some patients explore genicular artery embolization (GAE). GAE is a minimally invasive, image-guided procedure that targets the blood vessels associated with joint inflammation. It may help reduce knee pain in appropriate candidates and is performed on an outpatient basis. Many patients who explore GAE are navigating what is sometimes called the knee osteoarthritis treatment gap, the space between treatments that have stopped working well and a joint replacement they are not ready for.

When Knee Replacement May Be Considered

Knee replacement is a major surgery generally reserved for advanced cases, often Stage 4, where other options have not provided sufficient relief. It involves significant recovery time and is not the right fit for every patient or every stage of knee osteoarthritis. A pain management specialist can help you understand where your symptoms and imaging place you, and which early signs of knee arthritis you may have overlooked are worth discussing before considering surgery. Your specialist may also recommend imaging to evaluate knee arthritis to confirm your current stage before recommending next steps.

Knee Osteoarthritis Evaluation

Ready to Understand Your Stage of Knee Osteoarthritis?

Knowing your Kellgren-Lawrence grade is a helpful starting point, but it does not tell the whole story. Pain, mobility, and daily function vary widely between people at the same stage, which is why a specialist evaluation matters more than the number alone.

USA Pain Center specialists use advanced imaging and minimally invasive techniques to evaluate knee osteoarthritis at every stage and discuss whether options like genicular artery embolization may be appropriate for you.

FAQs About the Stages of Knee Osteoarthritis

What stage of osteoarthritis requires knee replacement?

Knee replacement is typically considered at Stage 4, when cartilage loss is advanced and conservative or minimally invasive options have not provided enough relief. It is not automatic at Stage 4; a specialist evaluation determines whether it is the right fit.

How do you walk with knee osteoarthritis?

Gentle, low-impact movement like walking is generally recommended over prolonged rest at every stage. Supportive shoes, a measured pace, and short rest breaks during flare-ups can help. A specialist or physical therapist can tailor guidance to your stage.

What are the symptoms of stage 4 osteoarthritis?

Stage 4 knee osteoarthritis often involves frequent or constant pain, persistent stiffness, swelling, reduced range of motion, and a grinding sensation during movement. Pain may continue even at rest and can disrupt sleep for some patients.

What are the symptoms of stage 3 knee osteoarthritis?

Stage 3 typically brings more frequent pain during walking, bending, or climbing stairs, along with swelling after activity and stiffness that takes longer to ease. A grinding or catching sensation during movement is also common.

What is end-stage knee osteoarthritis?

End-stage knee osteoarthritis refers to Stage 4 on the Kellgren-Lawrence scale, where cartilage loss is severe and joint space is significantly narrowed or gone. It describes imaging findings, not a guaranteed level of pain for every patient.

What is the Kellgren-Lawrence scale?

The Kellgren-Lawrence scale is the grading system physicians use to classify knee osteoarthritis severity from X-rays, ranging from Grade 0 (no signs) to Grade 4 (severe). It looks at joint space, bone spurs, and bone changes.

Can the stages of knee osteoarthritis be reversed?

Knee osteoarthritis is a progressive condition, and existing cartilage loss generally cannot be reversed. Treatment can help manage symptoms and may help slow further progression, allowing many patients to maintain function and reduce pain.

How is candidacy for GAE determined?

A pain management specialist evaluates your symptom history, prior treatments, and imaging to determine whether genicular artery embolization may be appropriate. Candidacy depends on your specific clinical picture rather than your stage number alone.

  1. Theis KA, Murphy LB, Guglielmo D, et al. “Prevalence of Arthritis and Arthritis-Attributable Activity Limitation, United States, 2019-2021.” MMWR Morb Mortal Wkly Rep. 2023;72(40):1101-1107. Centers for Disease Control and Prevention.
  2. Kellgren JH, Lawrence JS. “Radiological assessment of osteo-arthrosis.” Annals of the Rheumatic Diseases. 1957;16:494-502. As referenced in Kohn MD, et al., Classifications in Brief: Kellgren-Lawrence Classification of Osteoarthritis, National Institutes of Health (PMC).
  3. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). “Osteoarthritis.” National Institutes of Health.

Medical disclaimer: USA Pain Center content provides medical education only. It is not a diagnosis or treatment recommendation. Consult a pain management specialist for evaluation.

 

 

 

Non-Surgical Knee Pain Relief with Genicular Artery Embolization

At USA Pain Center, we specialize in treating knee pain caused by osteoarthritis, offering GAE (Genicular Artery Embolization) to help reduce knee pain and improve mobility. Whether you’re looking to avoid surgery or seeking relief from ongoing knee pain, USA Pain Center is here to help you get back to the activities you love.

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