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Person holding knee with bone-on-bone pain and wondering about GAE

For years, “bone-on-bone” knee arthritis has been treated as the end of the line — a phrase that often leads straight to joint replacement surgery. But what if there were another way to relieve the pain, improve mobility, and buy back your quality of life without going under the knife?

That’s exactly what many patients are discovering with Genicular Artery Embolization (GAE) — a minimally invasive procedure that targets knee pain at its source.

What “Bone-on-Bone” Really Means

When you hear “bone-on-bone,” it means the cartilage cushioning your knee joint has worn away. This loss leads to painful friction, inflammation, and swelling. Every step can feel stiff, achy, and exhausting. For many, walking, climbing stairs, or even standing becomes a daily challenge.

Traditional treatment options — from physical therapy to steroid injections — often provide temporary relief, while knee replacement surgery can be intimidating or risky, especially for older adults or those with other health conditions.

How GAE Works

GAE offers a groundbreaking alternative.
During the procedure, a doctor uses advanced imaging to guide a tiny catheter into the arteries that supply blood to the inflamed areas of your knee. By blocking these small arteries, blood flow — and therefore inflammation — is reduced.

Less inflammation means less pain, better mobility, and a renewed ability to live life comfortably.

Why Patients Are Turning to GAE

GAE is catching attention among both patients and orthopedic specialists for its benefits:

  • Minimally invasive – no large incisions or hospital stays

  • Quick recovery – most patients walk the same day

  • Low risk – ideal for those who aren’t candidates for surgery

  • Long-lasting relief – many report pain reduction for months to years

  • No implants or prosthetics – your own joint stays intact

This isn’t just pain management — it’s a new way to help your body heal itself by quieting inflammation at the source.

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What the Research Shows

Studies published in peer-reviewed journals have shown that GAE can significantly reduce knee pain and improve mobility in patients with moderate to severe osteoarthritis — even in those told they were “bone-on-bone.”

Many patients experience noticeable improvements within weeks, with results continuing to build over time.

Who’s a Good Candidate for GAE?

You may benefit from GAE if:

  • You’ve been told you have bone-on-bone arthritis

  • You’ve tried other treatments with little success

  • You’re not ready — or not eligible — for knee replacement

  • You want a non-surgical, outpatient option with minimal downtime

See If You Are a Candidate for GAE

Living Without Constant Knee Pain Is Possible

“Bone-on-bone” doesn’t have to mean “end of the road.” GAE is redefining what’s possible for people with chronic knee arthritis — offering hope, mobility, and independence without surgery.

If you’re struggling with daily pain or have been told surgery is your only option, ask a doctor if Genicular Artery Embolization is right for you.

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Non-Surgical Knee Pain Relief with Genicular Artery Embolization

At USA Pain Center, we specialize in treating knee pain caused by osteoarthritis, offering GAE (Genicular Artery Embolization) to help reduce knee pain and improve mobility. Whether you’re looking to avoid surgery or seeking relief from ongoing knee pain, USA Pain Center is here to help you get back to the activities you love.

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Give us a call now at

855-521-9500